发信人: think (齐天大圣), 信区: Biology
标 题: Finding the lost target
发信站: The unknown SPACE (Thu Feb 17 18:21:14 2000), 转信

Ramer MS et al Nature 403: 312-316 (2000)

When sensory nerve fibres are damaged in a peripheral nerve or a spinal root,
they can regenerate over long distances.

But when such regenerating fibres contact the spinal cord, they abruptly stop
growing ans seem unable to enter the CNS tissue.

The main reason for this is the barrier function of the junction between the
root and the CNS--the so-called dorsal root entry zone.

The study by Ramer shows that specific neurotrophic factors can inflence
the regenerating sensory fibres, allowing them to enter the spinal cord where
they terminate and establish functional connections.
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一半是火焰，一半是海水

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