发信人: golem (狗愣小岩), 信区: Biology
标 题: amazing new gene expression switch
发信站: The unknown SPACE (Wed Sep 4 13:59:29 2002), 转信

Peter Quail's group from Berkley employs light-wavelength sensitive proteins
(phytochrome) to obtain a potential light switched gene expression tool.
In plants, phytochromes exist in 2 states: Pr (sensitive to red light and turn
into Pfr), Pfr (receive far red light and turn into Pr). Only Pfr can bind to
a protein called PIF3.
Now they hook one half of GAL4 to phytochrome, another half to PIF3. Thus only
certain light could cause Pfr binding with PIF3, therefore bring together 2
halves of GAL4, which in turn turns on the GAL4 promoter regulated gene.
Since yeast is closely related to plant cell, this system is founded in yeast,
which makes it a great commercial promise.
cheers to the bioscience!


--
我被狂想的蛇带到冰雪的花园 在黑夜白昼时交渡羽毛
绿叶会变红 你是朗朗的风帆 鲜花变美酒 融合希望
是春带的雨 唤醒我萧尽的悲哀 是山野晚风 预知我未来
绿叶变红是展翅锋芒的渴望
也许你是我 我是你 只有你是我 我是你

※ 来源:．The unknown SPACE bbs.mit.edu．[FROM: 128.8.]