发信人: transmitter ((synatpic+vesicle+trafficking)), 信区: Biology
标 题: Re: 离子通道有什么好研究的?
发信站: The unknown SPACE (Sat Jan 11 18:05:01 2003), 站内信件
Ion channel is very important for the cell to control its resting potential,
propogate of action potential, etc.
One major question in this field is what is the structural and functional
relationship of ionchannels. For example, it is relative clear that the voltage
sensor S4 is critical for voltage dependent response, but how it changes its
structure during depolarization and how it links to the opening of the channel
pore are still unclear. Not until recently ( crystalgraphy of K channels from
bateria), people can only speculate those structural properties based on
indirect electrophysiological and biophysical approaches.
【 在 sunnyday (飞鸟) 的大作中提到: 】
: 调控啊,敏感度的改变啊,膜电位的改变啊。
: 我个人觉得无聊至极,但感兴趣的人不少。
: 【 在 scraper (削骨刀 爱你(.)(.)一万光年) 的大作中提到: 】
: : 就 chemical biology 而言, 有点好奇的说.
: : 其目标方向是什么?
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※ 来源:.The unknown SPACE bbs.mit.edu.[FROM: 152.3.]
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