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发信人: Morphin (莫非你是飞鸟；我养鱼), 信区: Biology
标 题: Re: MCBJC-call for discussion
发信站: The unknown SPACE (Mon Mar 17 15:33:31 2003) WWW-POST
i think in terms of synaptogenesis the neuro-muscular junction is well studied
in mice. so if one wants to study fish, he should definitely go for the
synaptogenesis in CNS.
Retino-tectal projection is a good system to study axon guidance. so is it for
the study of synaptic plasticity too. If i am gonna do that, probably I will
avoid those hot spots. In fact, our lab is gonna study the reticulo-spinal
curcuits in zebrafish. So I guess the synapsis formation in spinal cord may be
worth studying.
【 在 assasin (冷血---何时能被加热？) 的大作中提到: 】
: Which system in Zebrafish is good? Visual system? At stanford, Stephen Smith
: lab is studying synaptogenesis in zerafish optic tectum. But he is
definitely
: not the leader of this area. who else?
:
:
:
http://frd.stanford.edu/frd.lasso?-database=bluebook2.fmp&-layout=profile&-res
: ponse=profile.lasso&-recordID=32911&-search
:
:
: 【 在 Morphin (莫非你是飞鸟；我养鱼) 的大作中提到: 】
: : mammal is too complicate, try fish system.
: :
: : should not be very difficult to study synapses in fish.
: :
: : but Ig family is too diverse, or I am thinking to clone SYG-1 in fish.
: :
: : 【 在 kandel (迷路的小孩Mao JJ的弟弟) 的大作中提到: 】
: : : I read the paper briefly, and I'm still not clear what the authors want
to
: : : claim. But the paper is helpful to think the synapse formation issue
more
: : : broadly. that it's perhaps not only the pre or postsynaptic factors can
: : : tragger the specificity and differenticiation of pre/postsynapse,but
: : probably
: : : the envirmental factors can also contribute to this process. what's is
: : crucial
: : : is to clarify which is more predominant. But all the work is in C.E, for
: : : mammalian, we should get some powerful system to do this kind of
research.
: : Who
: : : has some smart idea to build up an powerful system or assay to
investigate
: : : this question in mamalian??
: : :
: : : as far as I know, even you block the mEPSC, and there are no spontanouse
: : : transmitter release, there are still clusters of AMPA receptors. how can
: : they
: : : achieve that?
: : :
: : :
: : :
: : : 【 在 assasin (冷血---何时能被加热？) 的大作中提到: 】
: : : : Marble, kandel and others, have u read the aper and have sth to say?
: : : :
: : : :
: : : : 【 在 assasin (冷血---何时能被加热？) 的大作中提到: 】
: : : : : MCBJC, cellular neurobiology, Mar. 10, 2003, by Assasin
: : : : :
: : : : : ***I decide to volunteer to make a presentation for the delayed and
: : missed
: : : : : MCBJC for this week. hope the folks who agreed to participate MCBJC
: take
: : : : their
: : : : : duty and keep it running.***
--
山脚一隅，草屋一间，良田三分，医书百卷，房前清溪，可凭垂钓，屋后药院，遍种百
草，采天地精华，解万家病痛，渔樵耕读，孜孜不倦，此愿得偿，我心足矣。
※ 来源:．The unknown SPACE bbs.mit.edu．[FROM: 141.211.]
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