发信人: ldg (三十三块★breathe), 信区: Biology
标 题: Re: 有没有一个软件?
发信站: Unknown Space - 未名空间 (Wed Sep 24 00:03:15 2003), 站内信件

dude, what you need is a phylogenetic tree, and to build such a tree,
you need to do the multiple sequence alignment first, edit the result
by removing those regions that are not well aligned(not well conserved)
then choose a phylogenetics software to build the tree. ( there're a
lot of softwares available based on quite different algorithms). I'm
not familiar with this, but I can tell you what someone else prefers.
For multiple sequence alignment, both clustalW and T-coffee are OK,
and the latter is a little bit more accurate.
For the tree building, go to

http://bioweb.pasteur.fr/seqanal/interfaces/bambe.html#_data

It's based on baysien statistics and doesn't need further evaluation.

【 在 batuloo (爱育栗拔力八达) 的大作中提到: 】
: 有没有一个软件 可以通过分子蛋白序列的相似性给出这些蛋白进化的分支图
: 假设这些蛋白的确有一个共同的祖先


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