发信人: jonzhang (清华MM的海鸥乔纳森), 信区: Biology
标 题: Re: progenitor cell and stem cell有什么不同
发信站: Unknown Space - 未名空间 (Wed Nov 10 10:35:40 2004) WWW-POST

No.

Now, it's suggested to use somatic stem cells concept than adult stem cells.

As far as I know, progenitor cells are of less differentiation
potential(multipotency, just many progenies but not all), while stem cells are
of pluripotency (All of the progenies). So in this matter, PC is considered
more committed, determined, or differentiated than SC. However, most time ppl
find adult stem cells which are really progenitor cells.

One also needs to clarify precursor cells (or simply precursors), while
progenitor cells are defined. Mostly accepted concept is that precursors are
committed cells to certain lineage of maybe one organ or one tissue type,
while progenitor cells can generate multiple lineages.

Self-renewal potential is another important consideration, while PC is
compared with SC. See Clonist's comments before.


【 在 lxyy (lxyy) 的大作中提到: 】
: is it adult stem cells
: 【 在 clonist (Epi) 的大作中提到: 】
: : generally speaking progenitor cells are dervied from stem cells. the fate
of
: : progenitor cells are more determined than stem cells and as a consequence
they
: : can only differetiated into a few cell types. while stem cells have much
: : more potential to differentiate into various cells and organs. it's all
about
: : potential.
: : 【 在 lxyy (lxyy) 的大作中提到: 】
:
:

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